Isaac Guerendo

Who Should I Start? Who Should I Sit? Some of the most common Week 1 fantasy football lineup decisions involve players like Christian McCaffrey, Ricky Pearsall, James Cook, Trey Benson, Braelon Allen, Rhamondre Stevenson, Isaac Guerendo, Chris Rodriguez Jr., Rachaad White.But not to worry, we are here to help make these decisions and build winning lineups in Week 1. Set your optimal fantasy football lineups for Week 1 of the 2025 NFL season. Our free Who Should I Start? tool will help make your... [Read More]

Second-year running back Isaac Guerendo opens the season third on the 49ers' depth chart, though he may already see more action than originally anticipated. Christian McCaffrey (calf) popped up on the team's injury report this week and is tagged as questionable for San Francisco's Week 1 matchup against the Seahawks. Guerendo's only route to fantasy relevance relies on CMC sitting. If that does happen, then he can be seen as a deep-league flex candidate. Brian Robinson Jr. will likely draw ... [Read More]

San Francisco 49ers running back Isaac Guerendo (shoulder) played at less than 100 percent during Saturday's preseason contest. Guerendo started the game, but re-aggravated his shoulder injury in the first quarter. Luckily, Guerendo was able to return to the game after getting looked at on the sideline. At the moment, all signs point to Guerendo being available for the season opener. However, his fantasy value is going to take a serious hit with Brian Robinson Jr. taking over as the RB2 in ... [Read More]

San Francisco 49ers running back Isaac Guerendo (shoulder) returned to training camp practice on Tuesday and was pretty active, according to Matt Maiocco of NBC Sports Bay Area. Guerendo will have more opportunities for reps with both Patrick Taylor Jr. (shoulder) and Corey Kiner (ankle) both injured. The 25-year-old missed a couple of weeks at camp with a shoulder injury but is now back in time to be ready for the Week 1 regular-season opener in two weeks. It remains to be seen if the ... [Read More]

Chris Allen highlights a running back poised to break out in the 2025 NFL season. [Read More]